Mar 20, 2024 | Current Functional Foods |
To evaluate the antioxidant and therapeutic potential of mango (Mangifera indica), a tropical fruit valued for its nutritional content, researchers from the University of Pittsburgh School of Medicine, USA, conducted a review. The review focused on evaluating mango’s role in supporting metabolic health through its bioactive compounds.
Using publications from the past 12 years sourced from Scopus and ScienceDirect databases, the study highlighted the significant antioxidant activity of mango, which is largely attributed to its high levels of phenolics and flavonoids. Key metabolites identified include glutathione and euxanthone, which contribute to the fruit’s antioxidant and anti-inflammatory effects.
The review also emphasized the role of mangiferin, a major bioactive compound in mango, which exhibits anti-diabetic effects by inhibiting intestinal enzymes such as sucrase and isomaltase, leading to reduced glucose absorption. Additionally, mango consumption was associated with improved insulin production, lowered blood sugar levels, and reduced lipid concentrations, benefits linked to its content of soluble fiber, polyphenols, quercetin, and beta-carotene.
The findings suggest that mango has potential as a functional food for dietary interventions aimed at metabolic health. The authors recommend mindful consumption strategies, such as avoiding high-glycemic combinations and integrating mango into a balanced lifestyle with regular physical activity.